ZAP-70 expression identifies a chronic lymphocytic leukemia subtype with unmutated immunoglobulin genes, inferior clinical outcome, and distinct gene expression profile.
By A. Wiestner, Andreas Rosenwald, T. Barry, George E. Wright, R. Davis, S. Henrickson, Hong Zhao, R. Ibbotson, J. Orchard, Z. Davis and 8 more. Blood, 2003
885 citations recorded by the source corpus.
Subfields: Genetics, Immunology, Pathology and Forensic Medicine
View Paper: https://www.semanticscholar.org/paper/44a299bb724fd0cb68bd73b8926af235a237ec81
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Citations in the corpus
- In vivo measurements document the dynamic cellular kinetics of chronic lymphocytic leukemia B cells. (2005, background): “Expression of ζ chain–associated protein 70 kDa (ZAP-70) mRNA or protein (11, 12) and the presence of CD38 on the leukemic cell surface also presage poor outcome (9, 13–16).”