IRAC: Mode of action classification and insecticide resistance management.

By T. C. Sparks, R. Nauen. Pesticide Biochemistry and Physiology, 2015

1,174 citations recorded by the source corpus.

Insecticide resistance is a long standing and expanding problem for pest arthropod control. Effective insecticide resistance management (IRM) is essential if the utility of current and future insecticides is to be preserved. Established in 1984, the Insecticide Resistance Action Committee (IRAC) is an international association of crop protection companies. IRAC serves as the Specialist Technical Group within CropLife International focused on ensuring the long term efficacy of insect, mite and tick control products through effective resistance management for sustainable agriculture and improved public health. A key function of IRAC is the continued development of the Mode of Action (MoA) classification scheme, which provides up-to-date information on the modes of action of new and established insecticides and acaricides and which serves as the basis for developing appropriate IRM strategies for crop protection and vector control. The IRAC MoA classification scheme covers more than 25 different modes of action and at least 55 different chemical classes. Diversity is the spice of resistance management by chemical means and thus it provides an approach to IRM providing a straightforward means to identify potential rotation/alternation options.

Subfields: Insect Science, Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/440da65e2d251d4a9d7b6ca9b7a027df279bfff5

How researchers see this paper

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In Insect Science

1. S. Dara
2. M. Meissle
3. Jörg Romeis
4. S. Naranjo
5. A. Shelton
6. G. Fitt
7. A. Tsagkarakou
8. Lauren J. Brzozowski

In Molecular Biology

1. M. Meissle
2. S. Dara
3. S. Naranjo
4. Jörg Romeis
5. A. Shelton
6. G. Fitt
7. Lauren J. Brzozowski
8. R. Nauen

In Plant Science

1. S. Dara
2. Jörg Romeis
3. M. Meissle
4. S. Naranjo
5. A. Shelton
6. G. Fitt
7. Lauren J. Brzozowski
8. R. Nauen

Citations in the corpus

• A review on biological interactions and management of the cotton bollworm, Helicoverpa armigera (Lepidoptera: Noctuidae) (2021, background): “Rotating through a number of insecticides with diverse modes of action (i.e. target sites) forms an essential part of insecticide resistance management programmes (Sparks & Nauen, 2015).”
• A Sustainable Agricultural Future Relies on the Transition to Organic Agroecological Pest Management (2018, background): “For weeds and fungi, these occurrences exceed 300 since 1960, and 1970, respectively [126].”
• Genetically engineered crops help support conservation biological control (2019, background): “, 2013), may play a significant role in limiting the number of cases of resistance to Bt plants to date, especially compared to the ever-increasing cases of resistance to broad-spectrum insecticides (Sparks and Nauen, 2015).”
• Insecticides, biologics and nematicides: Updates to IRAC's mode of action classification - a tool for resistance management. (2020, methodology): “In addition, as outlined previously (Nauen et al., 2012; Sparks and Nauen, 2015), IRAC's mission also includes encouraging the development and implementation of IRM strategies to maintain efficacy of current and future insect control compounds to support sustainable agriculture and improved public h”
• The New Integrated Pest Management Paradigm for the Modern Age (2019, positive): “Chemical pesticides are categorized into different groups based on their mode of action (IRAC 2018) and rotating chemicals from different mode of action groups is recommended to reduce the risk of resistance development (Sparks and Nauen 2015).”
• A four-year survey on insecticide resistance and likelihood of chemical control failure for tomato leaf miner Tuta absoluta in the European/Asian region (2017, background): “The phenomenon is gradually expanding, and to date more than 580 arthropod species have been reported to exhibit some form of resistance to chemical classes of insecticides, while resistance reports have been documented for at least 325 insecticides (Sparks and Nauen 2015).”