Fabrication of topologically complex three-dimensional microfluidic systems in PDMS by rapid prototyping.

By Janelle R. Anderson, D. Chiu, R. J. Jackman, Oksana Cherniavskaya, J. C. Mcdonald, Hongkai Wu, S. Whitesides, George M. Whitesides. Analytical Chemistry, 2000

705 citations recorded by the source corpus.

Subfields: Biomedical Engineering

View Paper: https://www.semanticscholar.org/paper/432e833ab82b1563b70591cda6e99215b72ebeec

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In Biomedical Engineering

Citations in the corpus

Chaotic mixing in three-dimensional microvascular networks fabricated by direct-write assembly (2003, methodology): “Our assembly route consists of three key steps: (1) scaffold fabrication by robotic deposition of a fugitive organic ink; (2) scaffold infiltration with an epoxy resin followed by curing and fugitive ink extraction; and (3) subsequent infiltration of a photocurable resin followed by masking and phot”
Direct, one-step molding of 3D-printed structures for convenient fabrication of truly 3D PDMS microfluidic chips (2015, methodology): “3b), which can represent any truly 3D microfluidic chip topologically (Anderson et al. 2000).”
UV/ozone modification of poly(dimethylsiloxane) microfluidic channels (2004, background): “Poly(dimethylsiloxane) (PDMS), in particular, generated interest due to its low cost and ease of fabrication, especially for rapid prototyping of microfluidic structures [12–18].”
A monolithic PDMS waveguide system fabricated using soft-lithography techniques (2005, methodology): “However, microscale PDMS structures have traditionally been fabricated using peel-off molds [16], [17].”
Microfluidics meets MEMS (2003, methodology): “used a similar approach yielding thin layers with through-holes and microstructuring on both sides, which were sealed with thicker PDMS slabs [95].”