Hepatocellular carcinoma: radio-frequency ablation of medium and large lesions.

By T. Livraghi, S. Goldberg, S. Lazzaroni, F. Meloni, T. Ierace, L. Solbiati, G. Gazelle. Radiology, 2000

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Guidelines and good clinical practice recommendations for Contrast Enhanced Ultrasound (CEUS) in the liver - update 2012: A WFUMB-EFSUMB initiative in cooperation with representatives of AFSUMB, AIUM, ASUM, FLAUS and ICUS. (2013, background): “Locoregional therapies, which conventionally include ablation, whatever the modality used, and transarterial chemo/radioem-bolization, play a key role in the management of patients with liver malignancies, both HCC and metastases [58, 98].”
Local Recurrence After Hepatic Radiofrequency Coagulation: Multivariate Meta-Analysis and Review of Contributing Factors (2005, background): “A second factor is that larger tumors more frequently have irregular borders than small tumors.(113) They also more”
Image-guided tumor ablation: standardization of terminology and reporting criteria--a 10-year update. (2014, background): “Although this phenomenon serves to protect blood vessels and prevent bleeding from large vessels, it is also a major source of incomplete tumor ablation in many studies involving thermal ablation (52).”