Late neurocognitive sequelae in survivors of brain tumours in childhood.

By R. Mulhern, T. Merchant, A. Gajjar, W. Reddick, L. Kun. The Lancet Oncology, 2004

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Reversible effect of X‐irradiation on proliferation, neurogenesis, and cell death in the dentate gyrus of adult mice (2007, neutral): “, 2000), and attentional and speed processing skills (Laack and Brown, 2004; Mulhern et al., 2004).”
Medical assessment of adverse health outcomes in long-term survivors of childhood cancer. (2007, result): “Neurocognitive and endocrine events have been intensively studied in patients with central nervous system tumors, and adverse outcomes are generally associated with whole-brain irradiation.(31,32,39,40) The increased risk of a high or severe burden of disease in survivors of irradiated brain tumors ”