A new antibiotic kills pathogens without detectable resistance
By L. Ling, T. Schneider, A. Peoples, Amy Spoering, Ina Engels, Brian P. Conlon, Anna Mueller, T. Schäberle, D. Hughes, S. Epstein and 11 more. Nature, 2015
2,297 citations recorded by the source corpus.
Subfields: Ecology, Molecular Biology, Pharmacology
View Paper: https://www.semanticscholar.org/paper/42c0f34058a4fec48e522688162b6ba16ba2eb31
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In Ecology
Citations in the corpus
- Antibacterial Coatings: Challenges, Perspectives, and Opportunities. (2015, background): “This was achieved by targeting less-mutable components of the bacteria (lipid precursors of cell wall components) rather than relatively mutable proteins [28].”
- A new antibiotic selectively kills Gram-negative pathogens (2019, neutral): “These include uncultured bacteria, from which teixobactin was discovered 16 ; and, surprisingly, several of the most abundant soil taxa – Acidobacteria, Verrucomicrobia, Rokubacteria and Gemmatimonadetes 33 .”
- Discovery of a structural class of antibiotics with explainable deep learning (2023, background): “Antibiotic candidates have been discovered in the past decade through various approaches based on natural product mining 2,3 , high-throughput screening 4 , evolution and phylogeny analyses 5,6 , structure-guided and rational design 7,8 , and in silico screens using machine learning 1,12–14 .”