Nilotinib (formerly AMN107), a highly selective BCR-ABL tyrosine kinase inhibitor, is effective in patients with Philadelphia chromosome-positive chronic myelogenous leukemia in chronic phase…
By H. Kantarjian, F. Giles, N. Gattermann, K. Bhalla, G. Alimena, F. Palandri, G. Ossenkoppele, F. Nicolini, S. O’Brien, M. Litzow and 8 more. Blood, 2007
765 citations recorded by the source corpus.
Subfields: Genetics, Hematology, Rheumatology
View Paper: https://www.semanticscholar.org/paper/425fc436550f680c9e315f164c75517c5ef29d99
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Citations in the corpus
- A Phase 2 Trial of Ponatinib in Philadelphia Chromosome–Positive Leukemias (2013, neutral): “Pancreatitis 19 (7) 17 (6) 7 (8) 5 (6) 3 (5) 2 (3) 0 0”
- Chronic myeloid leukemia: an update of concepts and management recommendations of European LeukemiaNet. (2009, background): “For all patients in CP, 1-year OS was 95%, and the proportion of patients remaining in MCgR after 1 year was 96%.(27) In patients in CP, the rate of nilotinib discontinuation for adverse events was 15% overall.”