Comparative genome analysis delimits a chromosomal domain and identifies key regulatory elements in the α globin cluster

By J. Flint, C. Tufarelli, J. Peden, K. Clark, R. Daniels, Ross C. Hardison, Webb Miller, S. Philipsen, K. C. Tan-Un, T. McMorrow and 4 more. 2001

150 citations recorded by the source corpus.

Subfields: Molecular Biology

View Paper: https://www.semanticscholar.org/paper/424ea5a83ec65b05ddf205328bdaeee8ac5a57e5

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In Molecular Biology

1. Martha L. Bulyk
2. D. Kleinjan
3. V. van Heyningen

Citations in the corpus

• Long-range control of gene expression: emerging mechanisms and disruption in disease. (2005, background): “In contrast to the b-globin gene cluster, the a-globin gene is located in a large region of “open” chromatin that contains a number of housekeeping genes (Flint et al. 2001).”
• Computational prediction of transcription-factor binding site locations (2003, background): “Thus, using fixed percentage identity cutoffs across entire genomes for considering regions conserved is likely to result in too much sequence being identified as functionally conserved in some regions and too little functionally conserved sequence being identified in other regions [61].”