Epidemiology of diabetic retinopathy, diabetic macular edema and related vision loss
By Ryan Lee, Tien Yin Wong, C. Sabanayagam. Eye and Vision, 2015
1,498 citations recorded by the source corpus.
Diabetic retinopathy (DR) is a leading cause of vision-loss globally. Of an estimated 285 million people with diabetes mellitus worldwide, approximately one third have signs of DR and of these, a further one third of DR is vision-threatening DR, including diabetic macular edema (DME). The identification of established modifiable risk factors for DR such as hyperglycemia and hypertension has provided the basis for risk factor control in preventing onset and progression of DR. Additional research investigating novel risk factors has improved our understanding of multiple biological pathways involved in the pathogenesis of DR and DME, especially those involved in inflammation and oxidative stress. Variations in DR prevalence between populations have also sparked interest in genetic studies to identify loci associated with disease susceptibility. In this review, major trends in the prevalence, incidence, progression and regression of DR and DME are explored, and gaps in literature identified. Established and novel risk factors are also extensively reviewed with a focus on landmark studies and updates from the recent literature.
Subfields: Clinical Biochemistry, Ophthalmology, Radiology, Nuclear Medicine and Imaging
View Paper: https://www.semanticscholar.org/paper/420ac49563c3dc2f55443ad88084619fdaac779e
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Radiology, Nuclear Medicine and Imaging
Citations in the corpus
- Optical coherence tomography angiography: A comprehensive review of current methods and clinical applications (2017, background): “Approximately 33% have signs of any DR and ~11% have vision-threatening DR (Lee et al., 2015).”
- Artificial intelligence in retina. (2018, background): “A third of an estimated 285 million people with diabetes have signs of DR and one third of them have vision-threatening DR (Lee et al., 2015).”