Isochorismate synthase is required to synthesize salicylic acid for plant defence

By M. Wildermuth, J. Dewdney, Gang Wu, Frederick M. Ausubel. Nature, 2001

2,280 citations recorded by the source corpus.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/41f030e3ab1b489248c3eb453c9b94587b7ffc8d

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In Molecular Biology

1. M. Ashraf
2. G. Noctor
3. N. Akram
4. Alisdair R. Fernie
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6. Zhixiang Chen
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In Plant Science

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6. C. Ryu
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8. S. He

Citations in the corpus

• Phenylpropanoid biosynthesis. (2010, positive): “In contrast, experimentalevidence from the Arabidopsis sid2 mutant, encoding isochorismate synthase 1 (ICS1) (Wildermuth et al., 2001; Strawn et al., 2007), as well as virus-mediated RNA-silencing in N. benthamiana (Catinotetal.,2008) suggest thatchorismateandICSmaybe central to and required for…”
• Catalase function in plants: a focus on Arabidopsis mutants as stress-mimic models. (2010, background): “, 2010), which is responsible for SA production in response to biotrophic pathogens (Wildermuth et al., 2001).”
• Bacterial Volatiles Induce Systemic Resistance in Arabidopsis1 (2004, background): “…propanoid component, salicylic acid (SA), appears to be a critical plant messenger of pathogen exposure and disease resistance (Durner et al., 1997; Wildermuth et al., 2001), whereas jasmonic acid (JA), a lipoxygenase pathway product, is a potent regulator that mediates plant responses to…”
• Functional Analysis of the Arabidopsis PAL Gene Family in Plant Growth, Development, and Response to Environmental Stress1[W][OA] (2010, background): “In ics1 mutants, total SA accumulation is only about 5% to 10% of wild-type levels after infection by the virulent biotroph Erysiphe or avirulent strains of Pseudomonas syringae (Wildermuth et al., 2001).”
• Magical mystery tour: Salicylic acid signalling (2015, background): “Both PTI and ETI lead to enhanced SA production via the ICS biosynthetic pathway (Wildermuth et al., 2001).”
• A Genomic Approach to Identify Regulatory Nodes in the Transcriptional Network of Systemic Acquired Resistance in Plants (2006, background): “Consistent with elevated SA levels, the SA biosynthesis gene ICS1 (encoding isochorismate synthase [10]) was clearly upregulated in wrky54 wrky70 (Figure 6B).”
• The salicylic acid loop in plant defense. (2003, background): “Preventing SA accumulation, by degrading it to catechol in transgenic plants that express the bacterial salicylate hydroxylase gene (NahG) [4,5] or by blocking SA synthesis [6 ,7], effectively blocks the activation of SA-dependent defense responses.”
• Salicylic acid beyond defence: its role in plant growth and development. (2011, background): “250 lg to 1 lg g 1 FW (Nawrath and Métraux, 1999; Wildermuth et al., 2001; Brodersen et al., 2005).”
• The Physiological, Biochemical and Molecular Roles of Brassinosteroids and Salicylic Acid in Plant Processes and Salt Tolerance (2010, background): “In Arabidopsis , ICS has been found to be involved in the biosynthesis of SA during the plant defense process (Wildermuth et al. , 2001).”