Sleep disturbances and depression: risk relationships for subsequent depression and therapeutic implications

By P. Franzen, Daniel J Buysse. Dialogues in Clinical Neuroscience, 2008

673 citations recorded by the source corpus.

The majority of individuals with depression experience sleep disturbances. Depression is also over-represented among populations with a variety of sleep disorders. Although sleep disturbances are typical features of depression, such symptoms sometimes appear prior to an episode of depression. The bidirectional associations between sleep disturbance (especially insomnia) and depression increase the difficulty of differentiating cause-and-effect relationships between them. Longitudinal studies have consistently identified insomnia as a risk factor for the development of a new-onset or recurrent depression, and this association has been identified in young, middle-aged, and older adults. Studies have also observed that the combination of insomnia and depression influences the trajectory of depression, increasing episode severity and duration as well as relapse rates. Fortunately, recent studies have demonstrated that both pharmacological and nonpharmacological interventions for insomnia may favorably reduce and possibly prevent depression. Together, these findings suggest that sleep-related symptoms that are present before, during, andlor after a depressive episode are potentially modifiable factors that may play an important role in achieving and maintaining depression remission.

Subfields: Cognitive Neuroscience, Endocrine and Autonomic Systems, Experimental and Cognitive Psychology

View Paper: https://www.semanticscholar.org/paper/415978c3a8c8247c6708c73ba3cb2c8eb8c7e11d

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In Cognitive Neuroscience

In Endocrine and Autonomic Systems

Matthew P. Walker

In Experimental and Cognitive Psychology

Citations in the corpus

Overnight Therapy? The Role of Sleep in Emotional Brain Processing (2009, background): “More recently, Franzen and Buysse (2008) measured the impact of total sleep deprivation on pupil diameter responses (a measure of autonomic reactivity) during a passive affective picture-viewing task containing positive, negative, and neutral stimuli.”
So depression is an inflammatory disease, but where does the inflammation come from? (2013, positive): “It is estimated that up to 80 to 90% of individuals who suffer from a MDD also experience sleep disturbances [194-196].”
The Role of Sleep in Emotional Brain Function (2014, background): “…entrance into REM sleep, (2) increased intensity of REM sleep (indexed in the number of rapid eye movements), and (3) longer duration of REM sleep periods (Armitage 2007, Buysse 2004, Franzen & Buysse 2008, Gottesmann & Gottesman 2007, Harvey et al 2003, Palagini et al 2013, Tsuno et al 2005).”