Prebiotic chemistry and the origin of the RNA world.

By L. Orgel. Critical reviews in biochemistry and molecular biology, 2004

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The eightfold path to non-enzymatic RNA replication (2012, background): “As recently as 2004, Leslie Orgel, one of the great founding fathers of the field of prebiotic chemistry, suggested that “the abiotic synthesis of RNA is so difficult that it is unclear that the RNA World could have evolved de novo on the primitive earth” [3].”
Common origins of RNA, protein and lipid precursors in a cyanosulfidic protometabolism (2015, background): “Thus, hydration of sodium and potassium cyanide gives the cyanide needed for the homologation chemistry, hydration of calcium cyanamide gives the cyanamide (2) needed for the synthesis of 2-aminooxazole (3) and hydration of calcium carbide gives acetylene (32), which, if it could be oxidatively coup”
Evolutionary Psychology as Maladapted Psychology (2007, background): “(Dennett 1995, 389) Dennett likely underestimates how difficult the problems are over the origin of life (see Orgel 2004 and Shapiro 2006 for overviews).”
Mineral Catalysis and Prebiotic Synthesis: Montmorillonite-Catalyzed Formation of RNA (2005, background): “…formation of RNA monomers is warranted, as there has been significant progress in the prebiotic formation of ribose (Müller et al. 1990; Zubay 1998; Ricardo et al. 2004; Springsteen and Joyce 2004) as well as in the synthesis of RNA by the reaction of monomers on an RNA template (e.g., Orgel 2004).”