Rates of hippocampal atrophy correlate with change in clinical status in aging and AD

By Clifford R. Jack Jr., R. C. Petersen, Yuecheng Xu, P. O'Brien, Glenn E. Smith, R. Ivnik, Brad Boeve, E. Tangalos, E. Kokmen. Neurology, 2000

941 citations recorded by the source corpus.

Subfields: Cognitive Neuroscience, Physical Therapy, Sports Therapy and Rehabilitation, Psychiatry and Mental health

View Paper: https://www.semanticscholar.org/paper/412175cf3fadbd098463cf78426d180e44d83935

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Citations in the corpus

Hippocampus and entorhinal cortex in mild cognitive impairment and early AD. (2004, methodology): “A few studies [9,10,12–14,23,24,28,29,47,48,51] have focused on MRI-based volumetric measurements of different brain regions in individuals classified for MCI in line or not with the criteria proposed by Mayo Clinic Alzheimer’s Disease Research Center (MCADRC) [39,40].”
MRI of hippocampal volume loss in early Alzheimer's disease in relation to ApoE genotype and biomarkers (2008, result): “…hippocampal loss (2.0–3.3% within 95% CI), in good agreement with reports of most other longitudinal MRI studies of mild cognitive impairment (Jack et al., 2000; Du et al., 2004; Fox et al., 2005; Hashimoto et al., 2005) that used much longer scan intervals, including two multicentre trials…”
Relationship between hippocampal volume and memory ability in healthy individuals across the lifespan: review and meta-analysis. (2004, result): “…but some studies suggest that cognitively normal adults who progress to MCI within a few years also have smaller-than-expected hippocampi at baseline as compared to cognitively normal adults who remain so over time (Jack et al., 2000; Marquis et al., 2002; see also Golomb et al., 1996).”
Patch-based segmentation using expert priors: Application to hippocampus and ventricle segmentation (2011, background): “Moreover, HC dysfunction is involved in a variety of diseases, including AD (Jack et al., 2000), posttraumatic stress disorder (Bremner et al., 1995), major depression (Bremner et al., 2000), schizophrenia (Buss et al., 2007; Tanskanen et al., 2005), and epilepsy (Bernasconi et al., 2003).”
RABBIT: Rapid Alignment of Brains by Building Intermediate Templates (2009, positive): “05 (false discover rate (FDR) corrected) (Bozzali et al., 2006; Busatto et al., 2003 ; Chetelat and Baron, 2003; Convit et al., 1997; Cuenod et al., 1993; De Santi et al., 2001; Du et al., 2001; Fan et al., 2008; Fox et al., 1996; Frisoni et al., 2007; Grundman et al., 2002; Jack et al., 2000; Jack ”
Spatial patterns of brain atrophy in MCI patients, identified via high-dimensional pattern classification, predict subsequent cognitive decline (2008, background): “…MRI-based studies of MCI patients have demonstrated brain atrophy mainly in medial temporal lobe structures (Convit et al., 1997; Jack et al., 1999; Jack et al., 2000; Xu et al., 2000; De Santi et al., 2001; Du et al., 2001; Grundman et al., 2002; Chetelat, 2003; Karas et al., 2004; Pennanen et…”
Early diagnosis of alzheimer's disease: contribution of structural neuroimaging (2003, background): “In 2000, the same team reported that the annual rate of Hcp volume loss was higher in converters than in nonconverters (Jack et al., 2000).”
Network Analysis of Intrinsic Functional Brain Connectivity in Alzheimer's Disease (2008, background): “brain structure [1,2] to more recent studies highlighting focal regions of abnormal brain function [3–6].”