Isolation and identification of the antialgal compound, harmane (1-methyl-β-carboline), produced by the algicidal bacterium, Pseudomonas sp. K44-1

By S. Kodani, Akiko Imoto, Atsushi Mitsutani, M. Murakami. Journal of Applied Phycology, 2002

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Antimicrobial screening and active compound isolation from marine bacterium NJ6-3-1 associated with the sponge Hymeniacidon perleve (2005, background): “Besides this antimicrobial activity, both harman and norharman also had activity against the cyanobacteria Anabaena cylindrical, Anabaena variabilis, Oscillatoria agardhii, Anacystis marina, Microcystis aeruginosa and Microcystis viridis, at a concentration of 30 lg/disk ( Kodani et al. 2002 ).”
Screening of microalgal culture media for the presence of algicidal compounds and isolation and identification of two bioactive metabolites, excreted by the cyanobacteria Nostoc insulare and Nodularia harveyana (2005, background): “Furthermore, Kodani et al. (2002) found no activity of norharmane against green algae.”