Rapid formation of plasma protein corona critically affects nanoparticle pathophysiology.
By S. Tenzer, D. Docter, Jörg Kuharev, A. Musyanovych, V. Fetz, Rouven Hecht, F. Schlenk, D. Fischer, K. Kiouptsi, C. Reinhardt and 5 more. Nature Nanotechnology, 2013
2,066 citations recorded by the source corpus.
Subfields: Biomaterials, Molecular Biology, Surfaces, Coatings and Films
View Paper: https://www.semanticscholar.org/paper/40e1d3f4f3c78c397594bfa5d00518bbaf0ff26a
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In Biomaterials
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In Surfaces, Coatings and Films
Citations in the corpus
- Impact of Microplastics and Nanoplastics on Human Health (2021, background): “Polystyrene nanoparticles may develop into varying forms of complex coronas, according to the conditions they are in [67].”
- Protein adsorption is required for stealth effect of poly(ethylene glycol)- and poly(phosphoester)-coated nanocarriers. (2016, background): “These results lead to fundamental insights that have to be considered for future nanocarrier design: (1) the stealth effect is not a polymer effect alone, but a secondary effect; (2) degradable poly(phosphoester)s are potential PEG alternatives; (3) the chemical structure of the stealth polymer can ”
- Control of Polymeric Nanoparticle Size to Improve Therapeutic Delivery (2015, background): “Protein coronas are formed within 30 seconds of contact with serum and can increase NP-apparent volume by 8-fold in just 10 minutes, leading to aggregation at later time points [57].”