Myofibroblast-mediated mechanisms of pathological remodelling of the heart

By K. Weber, Yao Sun, S. Bhattacharya, R. Ahokas, I. Gerling. Nature Reviews Cardiology, 2013

664 citations recorded by the source corpus.

Subfields: Cardiology and Cardiovascular Medicine, Oncology, Surgery

View Paper: https://www.semanticscholar.org/paper/409decb230dcae515d40052676a96780c2aeaf43

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cardiology and Cardiovascular Medicine

1. H. Ruskoaho
2. Virpi Talman

In Surgery

1. H. Ruskoaho
2. Virpi Talman

Citations in the corpus

• Non-coding RNAs in Development and Disease: Background, Mechanisms, and Therapeutic Approaches. (2016, background): “CFs showing these phenotypic and functional changes are called myofibroblasts and are particularly important during tissue repair and scarring after myocardial infarction (288).”
• Cardiac fibrosis in myocardial infarction—from repair and remodeling to regeneration (2016, background): “…that might traverse to the remote areas of the myocardium inducing activation and proliferation of local fibroblasts and increased collagen deposition in the interstitial compartment (interstitial fibrosis) and in the adventitia of coronary vessels (perivascular fibrosis; Weber et al. 2013).”
• Perivascular Gli1+ progenitors are key contributors to injury-induced organ fibrosis (2014, neutral): “…of myofibroblasts in cardiac fibrosis has been unclear for many years, although historic observations (Maccallum, 1899) and more recent work have suggested that perivascular cells might be involved (Weber et al., 2013), but no fate tracing data for pericytes or perivascular cells has ex- isted.”
• The Pathogenesis of Cardiac Fibrosis (2013, neutral): “Macrophages and fibroblasts infiltrating the injured heart produce renin and angiotensin-converting enzyme (ACe), molecules necessary for generation of angiotensin II [209].”
• Extracellular Matrix Communication and Turnover in Cardiac Physiology and Pathology (2015, neutral): “The ECM in the myocardium remote to the infarct zone also undergoes remodeling triggered by the ischemic injury (452).”