Dogma Disputed: Can Aggressively Lowering Blood Pressure in Hypertensive Patients with Coronary Artery Disease Be Dangerous?

By F. Messerli, G. Mancia, C. Conti, Ann C. Hewkin, S. Kupfer, Annette Champion, R. Kolloch, A. Bénétos, C. Pepine. Annals of Internal Medicine, 2006

743 citations recorded by the source corpus.

Subfields: Cardiology and Cardiovascular Medicine, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/408878d4e037913a009883e596a4f751298f9d6e

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cardiology and Cardiovascular Medicine

1. M. Woodward
2. Philippe van de Borne
3. Hani Jneid
4. F. Turnbull
5. E. Schiffrin
6. Allan S. Jaffe
7. H. S. Boudier

In Radiology, Nuclear Medicine and Imaging

1. M. Woodward
2. Kazem Rahimi

Citations in the corpus

• The 2015 Canadian Hypertension Education Program recommendations for blood pressure measurement, diagnosis, assessment of risk, prevention, and treatment of hypertension. (2013, result): “On the contrary, a number of the correlative analyses raising suspicion about the existence of a J-curve relationship between achieved BP and CV outcomes included a high proportion of CHD patients [317,318,322,323], and it is not unreasonable that, if a J-curve occurs, it may occur particularly in p”
• 2014 AHA/ACC guideline for the management of patients with non-ST-elevation acute coronary syndromes: executive summary: a report of the American College of Cardiology/American Heart Association Task Force on Practice Guidelines. (2014, methodology): “© American Heart Association, Inc and American College of Cardiology Foundation 133 Messerli 2006 (296) 16785477 Low BP with adverse events in CAD Multictr Ad hoc analysis 22576 BP reduction Sustained Rel.”
• ESH / ESC Guidelines for the management of arterial hypertension (2013, result): “lyses have also raised the point that a J-curve may exist for coronary events but not for strokes—but this is not a consistent finding in various trials.(317,318,324) –326 Whether or not the underlying high”
• Effects of intensive blood pressure lowering on cardiovascular and renal outcomes: updated systematic review and meta-analysis. (2016, background): “A number of recent post hoc analyses of clinical trial datasets have reignited concerns about the possibility of a J-curve for coronary disease at achieved systolic BP levels below 120 mmHg [39–41].”