Stability engineering of antibody single-chain Fv fragments.

By Arne Wörn, A. Plückthun. Journal of Molecular Biology, 2001

607 citations recorded by the source corpus.

Subfields: Molecular Biology, Radiology, Nuclear Medicine and Imaging

View Paper: https://www.semanticscholar.org/paper/4004a18ba3492a47d017febced400e13682d6f6a

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Molecular Biology

1. A. Teplyakov
2. Gary Gilliland
3. Dennis R. Goulet
4. M. Chiu

In Radiology, Nuclear Medicine and Imaging

1. A. Teplyakov
2. Gary Gilliland
3. Dennis R. Goulet
4. M. Chiu

Citations in the corpus

• Antibody Structure and Function: The Basis for Engineering Therapeutics (2019, background): “The stability of an antibody is influenced by a number of factors that can include: (1) core packing of individual domains that affects their intrinsic stability; (2) protein–protein interface interactions that have impact upon the HC and LC pairing; (3) burial of polar and charged residues; (4) hyd”