NUCLEAR ARCHITECTURE AND GENE REGULATION IN MAMMALIAN CELLS

By C. Cremer. 2001

2,320 citations recorded by the source corpus.

View Paper: https://www.semanticscholar.org/paper/3fffe9749fd622f63d483ef0e47f0438efb837c8

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Citations in the corpus

Intermingling of Chromosome Territories in Interphase Suggests Role in Translocations and Transcription-Dependent Associations (2006, background): “When the interphase nucleus forms, chromosomes partially decondense but still occupy distinct territories [1], which have nonrandom radial positions that are conserved through evolution [2–5].”
Three-Dimensional Maps of All Chromosomes in Human Male Fibroblast Nuclei and Prometaphase Rosettes (2005, unknown): “tion of chromatin in cycling and postmitotic cell types (for reviews see [2,3,4,5,6,7,8]).”
Chromosome territories. (2010, background): “The territorial organization of interphase chromosomes is now generally accepted as a basic principle of nuclear organization in both animals (Cremer and Cremer 2001) and plants (Shaw et al. 2002; Pecinka et al. 2004; Berr et al. 2006), and may even hold for single-cell eukaryotes, such as budding…”
Single-Cell and Single-Molecule Analysis of Gene Expression Regulation (2016, background): “Although DNA-FISH can assess only a few loci at the time, it established that chromosomes occupy discrete territories in the cell nucleus (39).”
Extensive Promoter-centered Chromatin Interactions Provide a Topological Basis for Transcription Regulation (2012, unknown): “Consequently, three-dimensional (3D) organization must have a role in the mechanisms for transcription regulation and coordination (Cremer and Cremer, 2001).”
A novel role for Xist RNA in the formation of a repressive nuclear compartment into which genes are recruited when silenced. (2006, background): “Indeed, Xist RNA coating is not essential for the maintenance of transcriptional repression in somatic cells; rather, multiple epigenetic marks act in synergy to ensure the stability of the inactive state (Czankovszki et al. 2001).”
CRISPR Inversion of CTCF Sites Alters Genome Topology and Enhancer/Promoter Function (2015, unknown): “Individual chromosomes occupy a distinct space in the nucleus, referred to as a ‘‘chromosome territory’’ (Cremer and Cremer, 2001), and within this region are relatively stable chromatin domains containing specific DNA-looping interactions between proximal promoters and distal regulatory DNA element”
Architectural protein subclasses shape 3D organization of genomes during lineage commitment. (2013, unknown): “Individual chromosomes occupy distinct spatial territories with respect to each other in interphase nuclei (Cremer and Cremer, 2001).”
Genome Sequencing of Pediatric Medulloblastoma Links Catastrophic DNA Rearrangements with TP53 Mutations (2012, unknown): “We note, however, that the known spatial organization of chromosomes maintained during interphase (Cremer and Cremer, 2001; Lichter et al., 1988) might similarly represent a structural basis for the local occurrence of DNA shattering.”
A three-dimensional map of the human genome at kilobase resolution reveals principles of chromatin looping (2014, unknown): “The spatial organization of the human genome is known to play an important role in the transcriptional control of genes (Cremer and Cremer, 2001; Sexton et al., 2007; Bickmore, 2013).”
Exploring the three-dimensional organization of genomes: interpreting chromatin interaction data (2013, background): “First, in interphase cells of many organisms, chromosomes do not readily mix but instead occupy their own separate territories 8 .”