Cross-frequency coupling supports multi-item working memory in the human hippocampus

By Nikolai Axmacher, Melanie M Henseler, Ole Jensen, I. Weinreich, Christian Erich Elger, J. Fell. Proceedings of the National Academy of Sciences of the United States of America, 2010

907 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Cognitive Neuroscience

View Paper: https://www.semanticscholar.org/paper/3fbcfd323dd5531b1d6ce30f9bb52e4dddc22385

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In Cellular and Molecular Neuroscience

In Cognitive Neuroscience

Citations in the corpus

Episodic Memory and Beyond: The Hippocampus and Neocortex in Transformation (2016, neutral): “Moreover, an intracranial EEG study found phase-amplitude coupling between theta and beta-gamma when faces were maintained in WM (Axmacher et al. 2010).”
Untangling cross-frequency coupling in neuroscience (2014, positive): “The modulation of CFC by the task or experimental condition has then been taken as an indication of its physiological role [4,5,7,28].”
Frontal Midline Theta Oscillations during Working Memory Maintenance and Episodic Encoding and Retrieval (2013, background): “A recent iEEG study provided initial support for the model by demonstrating that theta–gamma cross frequency coupling 2 supports multi-item WM maintenance (Axmacher et al., 2010).”
The Theta-Gamma Neural Code (2013, neutral): “More recently, the study of these oscillations in humans has become a focus of cognitive neuroscience (Axmacher et al., 2010; Canolty et al., 2006; Demiralp et al., 2007; Llinas and Ribary, 1993; Maris et al., 2011; Mormann et al., 2005; Sauseng et al., 2009; Voytek et al., 2010).”
Mechanisms of Gamma Oscillations (2012, background): “The magnitude of theta-gamma coupling in the hippocampal region varied with working memory load in patients implanted with depth electrodes (Axmacher et al. 2010).”
Dynamic Coding for Cognitive Control in Prefrontal Cortex (2013, background): “Phase synchrony has been implicated in WM (Axmacher et al., 2010; Buschman et al., 2011; Fell and Axmacher, 2011), and a recent study has further shown how rapid configuration of synchronized networks in PFC is specific to different rules states (Buschman et al., 2012).”
Gamma and beta bursts underlie working memory (2016, neutral): “Non-stationary memory delay activity has also been suggested by observations that PFC activity and gamma oscillations show slow frequency modulation (Jensen and Teshe, 2002; Palva et al., 2005; Watrous et al., 2013; Axmacher et al., 2010).”
Neural Cross-Frequency Coupling: Connecting Architectures, Mechanisms, and Functions. (2015, positive): “Interestingly, storage capacity could acutely be modulated by modifying the SO frequency, as observed during high-load working-memory tasks [9].”
Distributed theta networks support the control of working memory: Evidence from scalp and intracranial EEG (2025, unknown): “Theta rhythms are critical for distributed network integration, while high-frequency broadband activity facilitates local computations (Axmacher et al., 2010; Canolty et al., 2006; Jensen & Lisman, 2005).”
The Functional Interactions between Cortical Regions through Theta-Gamma Coupling during Resting-State and a Visual Working Memory Task (2022, unknown): “Previous studies found an association between TGC and WM [2,17,36–40], and it has been suggested that the power of gamma oscillations is systemically modulated over the course of the theta cycle, and that this interaction is a neurophysiologic process underlying WM [41,42].”