Complete humanization of the mouse immunoglobulin loci enables efficient therapeutic antibody discovery

By E-Chiang Lee, Q. Liang, Hanif Ali, Luke Bayliss, A. Beasley, Tara Bloomfield-Gerdes, Laura Bonoli, Richard J. P. Brown, J. Campbell, Adam J. Carpenter and 27 more. 2014

184 citations recorded by the source corpus.

Subfields: Molecular Biology, Oncology, Radiology, Nuclear Medicine and Imaging

Citations in the corpus

• Elicitation of Potent Neutralizing Antibody Responses by Designed Protein Nanoparticle Vaccines for SARS-CoV-2 (2020, neutral): “These results are consistent with the derivation of Darwinmice from the 129S7 and C57BL/6J genetic background (Lee et al., 2014), the latter of which has previously been shown to generate lower magnitude humoral responses compared to immunization of BALB/c mice (Corbett et al.”