Leisure Time Physical Activity of Moderate to Vigorous Intensity and Mortality: A Large Pooled Cohort Analysis

By S. Moore, Alpa V. Patel, C. Matthews, A. Berrington de González, Yikyung Park, H. Katki, M. Linet, E. Weiderpass, K. Visvanathan, K. Helzlsouer and 4 more. PLoS Medicine, 2012

650 citations recorded by the source corpus.

Analyzing data from over 650,000 individuals, Dr. Steven Moore and colleagues report that greater amounts of leisure-time physical activity were associated with higher life expectancy across a wide range of activity levels and body mass index groups.

Subfields: Health, Oncology, Physiology

View Paper: https://www.semanticscholar.org/paper/3f71ecae11c89d8e60745ecf0b7483c3d9fabbae

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Health

1. Massimo F. Piepoli

In Oncology

1. Adrian Bauman
2. Massimo F. Piepoli

In Physiology

1. Renee H. Rhodes
2. S. Bredin
3. Adrian Bauman
4. Massimo F. Piepoli
5. Ian Janssen

Citations in the corpus

• Exercise is the real polypill. (2013, background): “Higher MVPA levels [ 450 min/wk, clearly above the minimum international recommendations of 150 min/wk of MVPA (515)] are associated with longer life expectancy (317).”
• Leisure Time Physical Activity and Mortality: A Detailed Pooled Analysis of the Dose-Response Relationship (2015, neutral): “Heart disease 61 158 4380 (8) 15 450 (9) 15 462 (9) 12 512 (11) 12 445 (10) 777 (4) 132 (3)”
• 2016 European Guidelines on cardiovascular disease prevention in clinical practice (2017, positive): “1 Aerobic physical activity Aerobic PA, the most studied and recommended modality, with a beneficial dose– response effect on prognosis [259, 260, 268], consists of movements of large muscle mass in a rhythmic manner for a sustained period.”
• Physical activity: Health impact, prevalence, correlates and interventions (2017, background): “Engaging in ≤50% of the recommended 150 MVPA (i.e. 6–225 MET-min/wk of leisure time MVPA (roughly 75 min of brisk walking per week)) resulted in approximately two years of life gained (Moore et al., 2012).”
• Vascular Adaptation to Exercise in Humans: Role of Hemodynamic Stimuli. (2017, background): “Furthermore, the relationship between physical activity and CV risk exhibits a curvilinear dose-response pattern (319) with increasing, but diminishing, returns at higher activity levels (210).”