Osteonecrosis of the jaws associated with the use of bisphosphonates: a review of 63 cases.

By S. Ruggiero, B. Mehrotra, Tracey J Rosenberg, S. Engroff. Journal of oral and maxillofacial surgery, 2004

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Incidence, risk factors, and outcomes of osteonecrosis of the jaw: integrated analysis from three blinded active-controlled phase III trials in cancer patients with bone metastases. (2012, background): “Whereas the initial medical management of ONJ typically involved more aggressive surgical intervention [32], it has evolved to a less invasive interventional approach as awareness of the condition has increased.”
Severely suppressed bone turnover: a potential complication of alendronate therapy. (2005, background): “More recently, osteonecrosis of the jaw requiring surgical removal of affected tissue was reported in 59 patients who had received iv bisphosphonate for malignancy and in seven patients who took oral bisphosphonate for osteoporosis (24).”
Systematic Review: Bisphosphonates and Osteonecrosis of the Jaws (2006, background): “Treatment protocols have been outlined, but trials and outcomes of treatment and long-term follow-up data are not yet available (25, 27, 28, 65).”