A systematic review of mortality in schizophrenia: is the differential mortality gap worsening over time?

By S. Saha, D. Chant, John J. McGrath. Archives of General Psychiatry, 2007

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Biological Insights From 108 Schizophrenia-Associated Genetic Loci (2014, background): “Psychiatry 17, 996–1006 (2012). 50. Lewis, B. P., Burge, C. B. & Bartel, D. P. Conserved seed pairing, often flanked by adenosines, indicates that thousandsofhumangenesaremicroRNA targets.Cell 120, 15–20 (2005). Extended Data Table 1 | ALIGATOR and INRICH”
Schizophrenia: a concise overview of incidence, prevalence, and mortality. (2008, background): “Because our review found evidence to suggest that the case fatality rate in schizophrenia had remained stable in recent decades (29), the data suggest that the differential mortality gap has widened over time because the patient group did not share in the improved health of the general community.”
Royal Australian and New Zealand College of Psychiatrists clinical practice guidelines for the management of schizophrenia and related disorders (2016, background): “Suicide accounts for 28% of the excess mortality in people with schizophrenia, with aggregated SMR of 9.6 for men and 6.8 for women (Saha et al., 2007).”