MRI quantification of non‐Gaussian water diffusion by kurtosis analysis

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White matter characterization with diffusional kurtosis imaging (2011, methodology): “DKI is relatively easy to implement on clinical scanners and a typical DKI protocol requires 7 to 20 minutes for full brain coverage depending on the hardware and imaging parameters (Jensen and Helpern, 2010; Tabesh et al., 2011).”
White matter integrity, fiber count, and other fallacies: The do's and don'ts of diffusion MRI (2013, neutral): “kurtosis imaging (DKI) has been proposed (Jensen and Helpern, 2010; Jensen et al., 2005; Lu et al., 2006).”
Diffusion MRI at 25: Exploring brain tissue structure and function (2012, background): “But again, the relationship of those parameters with actual tissue parameters is not straightforward, unless strong and often unrealistic hypotheses are made about tissue structure or measurement conditions (Jensen and Helpern, 2010b).”
Body diffusion kurtosis imaging: Basic principles, applications, and considerations for clinical practice (2015, methodology): “Postprocessing software commonly applies a maximal possible upper limit for Kapp, above which the value is likely to represent an outlier due to motion, noise, or other artifact.(26) While Kapp theoretically may be negative, it will measure at least 0 in the setting of water exchange between multipl”