Bcl-2-mediated alterations in endoplasmic reticulum Ca2+ analyzed with an improved genetically encoded fluorescent sensor.

By A. Palmer, Can Jin, John Calvin Reed, Roger Tsien. Proceedings of the National Academy of Sciences of the United States of America, 2004

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Calcium and cancer: targeting Ca2+ transport (2007, background): “Although more difficult to measure than [Ca 2+ ] CYT , free resting Ca 2+ within the SR/ER is reported to be in the range of 100–500 μ”
Basis for a neuronal version of Grover's quantum algorithm (2014, background): “The fraction of unbound luminal Ca 2 + ranges from 100 to 700 μ M (Montero et al., 1995; Bygrave and Benedetti, 1996; Pinton et al., 1998; Alvarez and Montero, 2002; Bassik et al., 2004; Palmer et al., 2004; Verkhratsky, 2005).”
Calcium and apoptosis: ER-mitochondria Ca2+ transfer in the control of apoptosis (2008, background): “Finally, Tsien and colleagues (Palmer et al., 2004) showed that the green tea compound epigallocatechin gallate, known to bind and inactivate Bcl-2, reduced Ca2þ leakage from the ER and restored [Ca2þ ]ER of Bcl-2 overexpressing cells to values similar to those of control cells .”