NMDA receptor subunit diversity: impact on receptor properties, synaptic plasticity and disease

By P. Paoletti, C. Bellone, Qiang Zhou. Nature Reviews Neuroscience, 2013

2,390 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Molecular Biology

View Paper: https://www.semanticscholar.org/paper/3ee9bffd1987da813301078aa17f46942a7abe4e

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. L. Colucci-D'Amato
2. Todd D. Gould
3. Floriana Volpicelli
4. Luisa Speranza
5. E. Carafoli
6. Tito Calì
7. Denis Ottolini
8. M. Brini

In Molecular Biology

1. E. Pereira
2. Todd D. Gould
3. E. Albuquerque
4. E. Carafoli
5. Tito Calì
6. Denis Ottolini
7. M. Brini

Citations in the corpus

• Alpha-synuclein in Parkinson’s disease and other synucleinopathies: from overt neurodegeneration back to early synaptic dysfunction (2023, background): “SPNs were also recently investigated for the first time for detecting early synaptic transmission alterations exerted by α-syn Cell Death and Disease (2023) 14:176 oligomers, combining multiple techniques like electrophysiology optogenetics, immunofluorescence, and molecular and behavioral analyses ”
• Regulation of extrasynaptic signaling by polysialylated NCAM: Impact for synaptic plasticity and cognitive functions (2017, background): “NMDARs show a pronounced diversity in their subunit composition, pharmacological properties, interaction partners, and subcellular localization (Paoletti et al., 2013).”
• Ketamine and Ketamine Metabolite Pharmacology: Insights into Therapeutic Mechanisms (2018, background): “It is possible that the HNK-induced reduction of intracellular D-serine levels may also result in a reduction of extracellular levels of this amino acid.”
• Neuronal calcium signaling: function and dysfunction (2014, background): “The composition of the subunits of NMDARs is plastic, resulting in a large number of receptor subtypes with distinct biophysical, pharmacological, and signaling properties [16].”
• Neurotrophic Factor BDNF, Physiological Functions and Therapeutic Potential in Depression, Neurodegeneration and Brain Cancer (2020, background): “Activation of L-VGCC and NMDA receptors mediate intracellular Ca2+-signaling and regulate several aspects of brain functions (for review [34,35]).”