Genome sequence of the metazoan plant-parasitic nematode Meloidogyne incognita

By P. Abad, J. Gouzy, J. Aury, P. Castagnone-Sereno, Etienne G. J. Danchin, E. Deleury, L. Perfus-Barbeoch, Véronique Anthouard, F. Artiguenave, V. Blok and 44 more. Nature Biotechnology, 2008

1,214 citations recorded by the source corpus.

Plant-parasitic nematodes are major agricultural pests worldwide and novel approaches to control them are sorely needed. We report the draft genome sequence of the root-knot nematode Meloidogyne incognita, a biotrophic parasite of many crops, including tomato, cotton and coffee. Most of the assembled sequence of this asexually reproducing nematode, totaling 86 Mb, exists in pairs of homologous but divergent segments. This suggests that ancient allelic regions in M. incognita are evolving toward effective haploidy, permitting new mechanisms of adaptation. The number and diversity of plant cell wall–degrading enzymes in M. incognita is unprecedented in any animal for which a genome sequence is available, and may derive from multiple horizontal gene transfers from bacterial sources. Our results provide insights into the adaptations required by metazoans to successfully parasitize immunocompetent plants, and open the way for discovering new antiparasitic strategies.

Subfields: Molecular Biology, Plant Science

View Paper: https://www.semanticscholar.org/paper/3e170990153468c27fb62dfc9332928292ee347c

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Citations in the corpus

Targeted Delivery of Pesticides Using Biodegradable Polymeric Nanoparticles (2013, background): “M. incognita in the second-stage juveniles (J2) can penetrate the root and infect the plant (Abad et al. 2008).”
Comprehending crystalline β-carotene accumulation by comparing engineered cell models and the natural carotenoid-rich system of citrus (2011, neutral): “incognita and Meloidogyne hapla genomes (Abad et al., 2008; Opperman et al., 2008).”
Achievements and Challenges in Legume Breeding for Pest and Disease Resistance (2015, background): “…(Gardiner et al., 2013), Curtobacterium flaccumfaciens (Flanagan et al., 2013), Xylella fastidiosa (Zhang et al., 2011), Meloidogyne incognita (Abad et al., 2008), Meloidogyne hapla (Opperman et al., 2008), alfalfa mosaic virus (Cornelissen et al., 1983), cucumber mosaic virus (Owen et al.,…”
The threat of root‐knot nematodes (Meloidogyne spp.) in Africa: a review (2014, background): “Meloidogyne spp. cause an estimated annual loss of $157 billion globally (Abad et al., 2008).”
GenomeScope 2.0 and Smudgeplot for reference-free profiling of polyploid genomes (2020, background): “7 and 8).”
The Impact of Plant-Parasitic Nematodes on Agriculture and Methods of Control (2017, background): “Genomic analyses of root-knot nematodes have revealed the presence of a suite of enzymes called CAZymes (cellulases, xylanases and other glycosyl hydrolase family members (GHFs)) [11].”
Potential application spectrum of microbial proteases for clean and green industrial production (2017, background): “Depending on the species, a nematode may be beneficial or detrimental to plant health causing huge economic losses (Abad et al. 2008).”
WormBase: a comprehensive resource for nematode research (2009, background): “japonica; (2,3)]; the filarial agent Brugia malayi (4); the plant parasites Meloidogyne incognita (5) and Meloidogyne hapla (6); and the diplogastrid Pristionchus pacificus (7).”
The genome of the blood fluke Schistosoma mansoni (2009, neutral): “However, as lophotrochozoans they are evolutionarily distant from the previously sequenced parasitic nematodes Brugia 10 and Meloidogyne 11,12 (both ecdysozoans).”