Biocatalysis in Organic Chemistry and Biotechnology: Past, Present, and Future

By M. Reetz. 2013

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Strategies for the one-step immobilization-purification of enzymes as industrial biocatalysts. (2015, background): “…with outstanding prospects as catalysts in industrial processes which include high activity under very mild environmental conditions, high selectivity, and high specificity (Gröger and Hummel, 2014; Reetz, 2013; Schrittwieser and Resch, 2013; Teixeira et al., 2014; Wells and Meyer, 2014).”
Industrial applications of enzyme biocatalysis: Current status and future aspects. (2015, background): “This biotranformation process produces over 650,000 t annually in Japan (Ogawa and Shimizu, 2002; Groger et al., 2012; Reetz, 2013).”
Artificial Metalloenzymes: Reaction Scope and Optimization Strategies. (2018, background): “Reports to date have demonstrated that iterative targeted mutagenesis of residues proximal to metal cofactors (or at least their presumed location during catalysis) can improve ArM selectivity and activity.(7) While similar approaches have of course been used to optimize natural enzymes, the true”