Cisplatin and platinum drugs at the molecular level. (Review).

By T. Boulikas, Maria Vougiouka. Oncology Report, 2003

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Mechanisms in photodynamic therapy: part two-cellular signaling, cell metabolism and modes of cell death. (2005, background): “Radiation and chemotherapy tend to damage DNA and lead to apoptosis via cell-cycle checkpoints, growth arrest and p53 activation [6,7].”
A review of current nanoparticle and targeting moieties for the delivery of cancer therapeutics (2012, positive): “Similarly, cisplatin, a platinum-compound, modifies cellular DNA which activates signaling pathways that triggers apoptosis (Boulikas and Vougiouka, 2003).”