The Alzheimer’s Disease Centers’ Uniform Data Set (UDS): The Neuropsychological Test Battery
By S. Weintraub, David P. Salmon, N. Mercaldo, S. Ferris, N. Graff-Radford, H. Chui, Jeffrey L. Cummings, C. Decarli, N. Foster, Douglas Galasko and 5 more. Alzheimer Disease and Associated Disorders, 2009
807 citations recorded by the source corpus.
The neuropsychologic test battery from the Uniform Data Set (UDS) of the Alzheimer's Disease Centers (ADC) program of the National Institute on Aging consists of brief measures of attention, processing speed, executive function, episodic memory, and language. This paper describes development of the battery and preliminary data from the initial UDS evaluation of 3268 clinically cognitively normal men and women collected over the first 24 months of utilization. The subjects represent a sample of community-dwelling, individuals who volunteer for studies of cognitive aging. Subjects were considered “clinically cognitively normal” based on clinical assessment, including the Clinical Dementia Rating scale and the Functional Assessment Questionnaire. The results demonstrate performance on tests sensitive to cognitive aging and to the early stages of Alzheimer disease in a relatively well-educated sample. Regression models investigating the impact of age, education, and sex on test scores indicate that these variables will need to be incorporated in subsequent normative studies. Future plans include: (1) determining the psychometric properties of the battery; (2) establishing normative data, including norms for different ethnic minority groups; and (3) conducting longitudinal studies on cognitively normal subjects, individuals with mild cognitive impairment, and individuals with Alzheimer disease and other forms of dementia.
Subfields: Geriatrics and Gerontology, Physiology, Psychiatry and Mental health
View Paper: https://www.semanticscholar.org/paper/3c927a64c51e1240db7f2c1be1a4d44df237d0e2
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In Psychiatry and Mental health
Citations in the corpus
- OASIS-3: Longitudinal Neuroimaging, Clinical, and Cognitive Dataset for Normal Aging and Alzheimer Disease (2019, neutral): “Participants received an I.V. bolus injection of 5 mCi of [ 18 F]FDG followed by a dynamic 60min (consisting of 24 x 5 sec frames, 9 x 20 sec frames, 10 x 1 min frames and 9 x 5 min frames) PET acquisition.”
- Neuropsychological Criteria for Mild Cognitive Impairment Improves Diagnostic Precision, Biomarker Associations, and Progression Rates (2014, positive): “Each measure was converted to an age-corrected standard score using published normative data: Mayo Older Americans Normative Study data (n = 530; [36]) for the Rey AVLT and National Alzheimer’s Coordinating Center normative data (n = 3,286; [37, 38]) for the remaining neuropsychological measures.”