Magnetic nanoparticles for gene and drug delivery
By S. McBain, Humphrey H. P. Yiu, Jon Dobson. International Journal of Nanomedicine, 2008
756 citations recorded by the source corpus.
Investigations of magnetic micro- and nanoparticles for targeted drug delivery began over 30 years ago. Since that time, major progress has been made in particle design and synthesis techniques, however, very few clinical trials have taken place. Here we review advances in magnetic nanoparticle design, in vitro and animal experiments with magnetic nanoparticle-based drug and gene delivery, and clinical trials of drug targeting.
Subfields: Biomaterials, Biomedical Engineering, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/3c57df0a172e1a92df9a0e124dd8f49df75bce3a
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In Biomaterials
In Biomedical Engineering
In Molecular Biology
Citations in the corpus
- Magnetic nanoparticles and targeted drug delivering. (2010, background): “The importance of targeted drug delivery and targeted drug therapy is to transport a drug directly to the centre of the disease under various conditions and thereby treat it deliberately, with no effects on the body.”
- To exploit the tumor microenvironment: Passive and active tumor targeting of nanocarriers for anti-cancer drug delivery. (2010, background): “Under the influence of external magnets, it is possible to guide nanoparticles to a particular targeted site [98,99].”
- Green synthesis of metal and metal oxide nanoparticles from plant leaf extracts and their applications: A review (2020, background): “MNPs and MONPs have many applications such as catalysts [19]; drug delivery systems [20]; boosting contrast agents [21]; active food packaging materials [22]; components pointing to nano-biosensor construction [23]; gene transfer”