Pathogenesis and Pathophysiology of Endometriosis

By R. Burney, L. Giudice. Fertility and Sterility, 2012

1,457 citations recorded by the source corpus.

Originally described over three hundred years ago, endometriosis is classically defined by the presence of endometrial glands and stroma in extrauterine locations. Endometriosis is an inflammatory, estrogen dependent condition associated with pelvic pain and infertility. This work reviews the disease process from theories regarding origin to the molecular basis for disease sequelae. A thorough understanding of the histopathogenesis and pathophysiology of endometriosis is essential toward the development of novel diagnostic and treatment approaches for this debilitating condition.

Subfields: Cardiology and Cardiovascular Medicine

View Paper: https://www.semanticscholar.org/paper/3bfb944d53a5aadd8d2685ea434e91f6843e629d

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Citations in the corpus

• What we know about primary dysmenorrhea today: a critical review. (2015, background): “Importantly, the enhanced pain sensitivity is evident even in phases of the menstrual cycle when women are not experiencing menstrual pain, illustrating that long-term differences in pain perception extend outside of the painful menstruation phase.”