Dual enzyme-like activities of iron oxide nanoparticles and their implication for diminishing cytotoxicity.

By Zhongwen Chen, Jun-Jie Yin, Yu‐Ting Zhou, Yu Zhang, Lina Song, Mengjie Song, Sunling Hu, Ning Gu. ACS Nano, 2012

781 citations recorded by the source corpus.

Subfields: Biomaterials, Materials Chemistry

View Paper: https://www.semanticscholar.org/paper/0f649e4f1e30650a57b0f2ba950f540e3b0c4033

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Biomaterials

1. Ning Gu
2. F. Xiong
3. Fang Yang
4. Dong Liu

Citations in the corpus

• Bacterial synthesis of nanoparticles: A green approach (2020, background): “…with enzyme-mimetic properties, as a potential alternative to natural enzymes and for use in immunoassay, biosensor, oncotherapy, pharmacy, food industry, ecology, etc. (Chen et al., 2012, 2014; Fu, 2014; Lu et al., 2015; Li & Zhang, 2016; Tsekhmistrenko et al., 2018; Mu et al., 2019).”
• Seed Priming with Iron Oxide Nanoparticles Triggers Iron Acquisition and Biofortification in Wheat (Triticum aestivum L.) Grains (2018, background): “This could be due to the fact that the engineered iron oxide nanoparticles are known to produce free radicals in the microenvironment which drastically enhances the H2O2 induced cell damage (Chen et al. 2012).”
• Several lines of antioxidant defense against oxidative stress: antioxidant enzymes, nanomaterials with multiple enzyme-mimicking activities, and low-molecular-weight antioxidants (2024, background): “…the help of electron paramagnetic resonance (EPR) spin trapping spectroscopy, it was demonstrated that Fe 3 O 4 and γ-Fe 2 O 3 nanoparticles exhibit enhanced peroxidase-like activity at acidic pH (pH = 4.8), while catalase-like activity was observed near physiological pH (7.4) (Chen et al. 2012).”
• The Smart Drug Delivery System and Its Clinical Potential (2016, background): “Magnetic stimuli may provide a non-invasive approach to temporally and spatially control of the carriers to the targets and release drugs under programmable exposure of external magnetic field [47-49].”