The family based association test method: strategies for studying general genotype–phenotype associations

By S. Horvath, Xin Xu, Nan M. Laird. European Journal of Human Genetics, 2001

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Large-Scale Discovery of Disease-Disease and Disease-Gene Associations (2016, background): “Establishing a relationship between a phenotype and its associated genes is a major component of gene discovery and allows biomedical scientists to gain a deeper understanding of the condition and a potential cure at its very origin 16 .”
Applications of Linkage Disequilibrium and Association Mapping in Maize (2009, neutral): “1999) and family-based association tests (FBATs) (Laird et al. 2000; Lake et al. 2000; Horvath et al. 2001; Lange et al. 2003; Herbert et al. 2006; Laird and Lange 2006).”
Prioritizing GWAS results: A review of statistical methods and recommendations for their application. (2010, background): “Their new formulation owes an intellectual debt to the FBAT (family-based association test) method.(65,66) Other innovations include introduction of entropy and conditional entropy measures of interaction(67,68); exploitation of proximity measures between individuals; and application of neural netwo”