The inflammatory response in stroke.

By Qing Wang, X. Tang, M. Yenari. Journal of Neuroimmunology, 2007

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Regulatory T cells are key cerebroprotective immunomodulators in acute experimental stroke (2009, background): “Upregulation of cerebral proinflammatory cytokines, activation of local microglia and systemic lymphocytes and invasion of leukocytes in the brain contribute substantially to ischemic brain damag”
Neuroprotection for ischemic stroke: past, present and future. (2008, background): “…Fukunaga et al., 2003; Perez-Pinzon et al., 2005; Zhao et al., 2006) Signaling: inflammatory mediators (cytokines, chemokines) (Planas et al., 2006; Wang et al., 2007) Protective influence of mild to moderate hypothermia (Barone et al., 1997b; Busto et al., 1998; Erecinska et al., 2003; Gunn et…”
Regulation of innate immune responses in the brain (2009, background): “Indeed, the infiltration of monocytes, neutrophils and lymphocytes into the CNS contributes to post-ischaemic injury and their recruitment largely depends on the early release of pro-inflammatory molecules by resident cell”