The salience network is responsible for switching between the default mode network and the central executive network: Replication from DCM
By Nia Goulden, Aygul Khusnulina, Nicholas J. Davis, Robert M. Bracewell, Arun L. W. Bokde, Jonathan P. McNulty, Paul G. Mullins. NeuroImage, 2014
758 citations recorded by the source corpus.
With the advent of new analysis methods in neuroimaging that involve independent component analysis (ICA) and dynamic causal modelling (DCM), investigations have focused on measuring both the activity and connectivity of specific brain networks. In this study we combined DCM with spatial ICA to investigate network switching in the brain. Using time courses determined by ICA in our dynamic causal models, we focused on the dynamics of switching between the default mode network (DMN), the network which is active when the brain is not engaging in a specific task, and the central executive network (CEN), which is active when the brain is engaging in a task requiring attention. Previous work using Granger causality methods has shown that regions of the brain which respond to the degree of subjective salience of a stimulus, the salience network, are responsible for switching between the DMN and the CEN (Sridharan et al., 2008). In this work we apply DCM to ICA time courses representing these networks in resting state data. In order to test the repeatability of our work we applied this to two independent datasets. This work confirms that the salience network drives the switching between default mode and central executive networks and that our novel technique is repeatable.
Subfields: Cognitive Neuroscience
View Paper: https://www.semanticscholar.org/paper/3b1c02c866257ca25a2c4e88d0890e2d3805c002
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Citations in the corpus
- A guide to group effective connectivity analysis, part 1: First level analysis with DCM for fMRI (2019, methodology): “This means that stochastic DCM can be used to model resting state (e.g. Bastos-Leite et al., 2014; Goulden et al., 2014; Dirkx et al., 2016) as well as task-based fMRI studies where endogenous fluctuations are important (e.”
- Nurturing Nature: How Brain Development Is Inherently Social and Emotional, and What This Means for Education (2019, methodology): “Critically, the Default Mode Network is recruited when task-oriented, goal-directed behavior and externally directed attention and perception are attenuated; it does not readily coactivate with the Executive Control Network.”