Biomedical applications of hydrogels: A review of patents and commercial products

By E. Caló, V. Khutoryanskiy. 2015

2,273 citations recorded by the source corpus.

Hydrogels have become very popular due to their unique properties such as high water content, softness, flexibility and biocompatibility. Natural and synthetic hydrophilic polymers can be physically or chemically cross-linked in order to produce hydrogels. Their resemblance to living tissue opens up many opportunities for applications in biomedical areas. Currently, hydrogels are used for manufacturing contact lenses, hygiene products, tissue engineering scaffolds, drug delivery systems and wound dressings. This review provides an analysis of their main characteristics and biomedical applications. From Wichterle’s pioneering work to the most recent hydrogel-based inventions and products on the market, it provides the reader with a detailed introduction to the topic and perspective on further potential developments.

Subfields: Biomaterials, Biomedical Engineering, Molecular Medicine

View Paper: https://www.semanticscholar.org/paper/3ae655b5f7d4e0df94376fdfeb7b6a65bd495c4a

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In Biomaterials

In Biomedical Engineering

Citations in the corpus

Applications of nanocomposite hydrogels for biomedical engineering and environmental protection (2018, background): “In particular, molecular network of nanocomposite hydrogel has been covalently cross-linked with nanoparticles (Caló and Khutoryanskiy 2015).”
Polymer-Based Hydrogels Applied in Drug Delivery: An Overview (2023, background): “The design and formulation of polymer-based hydrogels continues to be an active area of research, aiming to develop advanced materials with enhanced properties and functionalities to meet the demands of biomedical applications [9,17,42,43,56,70,87,88,108].”
pH Sensitive Hydrogels in Drug Delivery: Brief History, Properties, Swelling, and Release Mechanism, Material Selection and Applications (2017, background): “The release of loaded drug may take place by several mechanisms such as swelling control, diffusion control, environmental sensitivity control, and chemically controlled release [23].”
Hydrogels and Their Applications in Targeted Drug Delivery (2019, background): “Uniform dissolution or dispersion of the drug throughout the 3D structure of the hydrogel is achieved using matrix delivery (reprinted (adapted) with permission from [3]; the article is open access and the content reusable).”
Current hydrogel advances in physicochemical and biological response-driven biomedical application diversity (2021, background): “In terms of clinical translation, many facial corrections and esthetic hydrogel-based products have been approved by Food and Drug Administration (FDA).(68,69) Some clinical trials also have confirmed the effectiveness of hydrogel-based therapy in various areas: knee osteoarthritis, spinal fusion, a”