The impact of FLT3 internal tandem duplication mutant level, number, size, and interaction with NPM1 mutations in a large cohort of young adult patients with acute myeloid leukemia.

By R. Gale, Claire L. Green, C. Allen, A. Mead, A. Burnett, R. Hills, D. Linch. Blood, 2008

763 citations recorded by the source corpus.

Subfields: Hematology

View Paper: https://www.semanticscholar.org/paper/3adb592616313faafeb8099a2fdbe685fc562a75

Citations in the corpus

• Therapeutic advances in acute myeloid leukemia. (2011, neutral): “Further prognostic subdivision is proposed based on the FLT3-ITD to FLT3 wild type (WT) allele ratio (high ratio conferring higher risk), the length of the duplication (increasing size associated with decreasing survival), and the location of the insertion (the more C-terminal, the longer the insert”