mGluR2 postsynaptically senses granule cell inputs at Golgi cell synapses.

By Dai Watanabe, S. Nakanishi. 2003

98 citations recorded by the source corpus.

Subfields: Cellular and Molecular Neuroscience, Sensory Systems

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Cellular and Molecular Neuroscience

1. Egidio D'Angelo
2. Paul Dean
3. Christian A. Rössert
4. John Porrill

In Sensory Systems

1. Egidio D'Angelo
2. Paul Dean
3. Christian A. Rössert
4. John Porrill

Citations in the corpus

• Re-evaluating circuit mechanisms underlying pattern separation (2019, neutral): “However, indirect excitatory feedback could occur through the inhibition of Golgi cells via metabotropic glutamate receptor activated Gprotein-coupled inwardly-rectifying potassium (GIRK) channels (Watanabe and Nakanishi, 2003).”
• Granule Cell Ascending Axon Excitatory Synapses onto Golgi Cells Implement a Potent Feedback Circuit in the Cerebellar Granular Layer (2013, background): “…studies of GrC inputs to GoCs mostly used extracellular stimulation in the ML (Bureau et al., 2000; Misra et al., 2000; Brickley et al., 2003; Watanabe and Nakanishi, 2003; Beierlein et al., 2007; Menuz et al., 2008; Robberechts et al., 2010), which does not allow separation of local from…”
• Identification of an inhibitory circuit that regulates cerebellar Golgi cell activity (2012, unknown): “Previous studies have shown that Golgi cells are the only inhibitory cell in the cerebellar cortex to express mGluR2 and that the selective group II mGluR agonist (2R,4R)-APDC strongly hyperpolarizes Golgi cells to silence their spontaneous spiking (Ohishi et al., 1994; Watanabe and Nakanishi, 2003)”
• At the Edge of Chaos: How Cerebellar Granular Layer Network Dynamics Can Provide the Basis for Temporal Filters (2015, methodology): “Since some Golgi cells have been shown not to express mGluR2 [31,51] we further tested the effect of only 50% of the Golgi cells receiving mGluR2 inhibition (Fig 7A, solid red lines).”
• Purkinje cells directly inhibit granule cells in specialized regions of the cerebellar cortex (2016, unknown): “Since neither MLIs nor PCs make direct connections to GoCs to provide feedback control of the input layer (Hull and Regehr, 2012; Witter et al., 2016), it is thought that cerebellar computations are carried out sequentially: inputs are first processed in the GrC layer and then interpreted by the PCs”