Mitochondria: master regulators of danger signalling
By L. Galluzzi, Oliver Kepp, Guido Kroemer. Nature reviews. Molecular cell biology, 2012
712 citations recorded by the source corpus.
Subfields: Endocrinology, Epidemiology, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/3ad6385e80bf0a68206c199143d192ef94993ab4
How researchers see this paper
The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.
In Endocrinology
In Epidemiology
- L. Galluzzi
- Guido Kroemer
- L. Zitvogel
- Oliver Kepp
- C. Brenner
- Edward J. Pearce
- Erika L. Pearce
- Beth Levine
In Molecular Biology
- Guido Kroemer
- L. Galluzzi
- John C. Marioni
- Sarah A. Teichmann
- Oliver Kepp
- C. Brenner
- L. Zitvogel
- Davis J. McCarthy
Citations in the corpus
- Metabolic Pathways In Immune Cell Activation And Quiescence (2013, background): “The presence of nonfunctional mitochondria can be dangerous because a loss of mitochondrial membrane potential can lead to the release of cytochrome C into the cytoplasm and the initiation of apoptosis (Galluzzi et al., 2012; van Raam et al., 2006).”
- Mitochondrial dysfunction: mechanisms and advances in therapy (2024, background): “212 In the mitochondrial electron transport chain, 11 potential sites have been delineated where electron leakage may occur, generating superoxide (O 2) and/or hydrogen peroxide (H 2 O 2 ).”
- Mechanism of action of conventional and targeted anticancer therapies: reinstating immunosurveillance. (2013, background): “A comprehensive compendium of chemotherapeutic agents that mediate immunostimulatory effects can be found in Galluzzi et al. (2012c) and Vanneman and Dranoff, (2012).”
- Mitochondrial metabolism and cancer (2017, background): “On the one hand, mitochondria are the source of many danger signals released by cancer cells as they die, and these signals are crucial for the activation of dendritic cells to optimally prime tumor-targeting immune responses [187].”
- Necroptosis: Mechanisms and Relevance to Disease (2016, neutral): “Thus, at odds with several (but not all) other RCD variants (30), necroptosis may not depend on mitochondria.”
- Classification of low quality cells from single-cell RNA-seq data (2016, background): “There is an extensive literature on the relationship between mtDNA, mitochondrially localized proteins, and cell death [34, 35].”