A Living Biobank of Breast Cancer Organoids Captures Disease Heterogeneity.
By Norman Sachs, Joep de Ligt, O. Kopper, E. Gogola, G. Bounova, F. Weeber, Anjali Vanita Balgobind, K. Wind, A. Gračanin, H. Begthel and 21 more. Cell, 2018
1,673 citations recorded by the source corpus.
Subfields: Cancer Research, Oncology
View Paper: https://www.semanticscholar.org/paper/3a51cd37d4e2833fcf13144c3229769aeb6f87e9
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In Cancer Research
In Oncology
Citations in the corpus
- A Patient-Derived Glioblastoma Organoid Model and Biobank Recapitulates Inter- and Intra-tumoral Heterogeneity. (2019, background): “Organoids have since been applied to model various cancers, including pancreatic, prostate, liver, breast, bladder, ovarian, and gastrointestinal cancers (Boj et al., 2015; Broutier et al., 2017; Gao et al., 2014; Kopper et al., 2019; Lee et al., 2018; Sachs et al., 2018; Yan et al., 2018).”
- Breast cancer development and progression: Risk factors, cancer stem cells, signaling pathways, genomics, and molecular pathogenesis (2018, background): “Recent studies have been able to exceed prior limitations to mouse models for cellular lineage-tracing to using patient-derived breast cancer organoids.(69) The construction of a living breast cancer organoid biobank is one such project that may be employed for research on cancer cell heterogeneity ”