Increased risk of cognitive impairment or dementia in women who underwent oophorectomy before menopause

By Walter A. Rocca, J. H. Bower, D. Maraganore, J. Ahlskog, B. Grossardt, M. D. Andrade, L. J. Melton. Neurology, 2007

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Understanding the impact of sex and gender in Alzheimer's disease: A call to action (2018, neutral): “[85] Rocca WA, Bower JH, Maraganore DM, Ahlskog JE, Grossardt BR,”
ESHRE Guideline: management of women with premature ovarian insufficiency. (2016, background): “The possible detrimental effect on cognition should be discussed when planning hysterectomy and/or oophorectomy under the age of 50 years, especially for prophylactic reasons (Rocca et al., 2007; Rocca et al., 2008; Vearncombe and Pachana, 2009; Phung et al., 2010; Bove et al., 2014) D”
2016 Alzheimer's disease facts and figures (2016, positive): “Nonetheless, evidence does not support the use of supplemental estrogen after menopause to prevent Alzheimer’s [144,145], although some research suggests possible benefits for women who have had their ovaries removed [146,147].”
Clinical epidemiology of Alzheimer’s disease: assessing sex and gender differences (2014, positive): “utilizing HRT at least until the age of natural menopause (approximately 51 years), did not experience an increased risk of AD.(123) In contrast to these studies showing a beneficial effect of estrogen use, the Women’s Health Initiative Memory Study (WHIMS),(124) a large randomized clinical trial of”