A novel algorithm for reliable detection of human papillomavirus in paraffin embedded head and neck cancer specimen

By S. Smeets, A. Hesselink, E. M. Speel, A. Haesevoets, P. Snijders, M. Pawlita, C. Meijer, B. Braakhuis, C. R. Leemans, Ruud H. Brakenhoff. International Journal of Cancer, 2007

786 citations recorded by the source corpus.

Subfields: Epidemiology, Otorhinolaryngology, Surgery

View Paper: https://www.semanticscholar.org/paper/394b85c7e874e247c48d56ed63f692cdbc35f384

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

In Epidemiology

1. Ruud H. Brakenhoff
2. C. R. Leemans
3. B. Braakhuis
4. S. Marur
5. A. Forastiere

In Otorhinolaryngology

1. S. Marur
2. A. Forastiere

In Surgery

1. S. Marur

Citations in the corpus

• The molecular biology of head and neck cancer (2011, result): “It was shown that an algorithm of p16 INK4A (also known as CDKN2A) immunostaining (a surrogate marker for HPV infection) combined with HPV DNA PCR on the p16 INK4A -positive cases gave reliable results on archival FFPE specimen”
• Head and Neck Squamous Cell Carcinoma: Update on Epidemiology, Diagnosis, and Treatment. (2016, methodology): “Currently, screening tumor tissue with p16 IHC first followed by HPV-specific testing with ISH or PCR is recommended.(17)”