A single-cell atlas of entorhinal cortex from individuals with Alzheimer’s disease reveals cell-type-specific gene expression regulation

By Alexandra Grubman, Gabriel Chew, John F. Ouyang, Gui-zhi Sun, Xin Yi Choo, C. Mclean, Rebecca K. Simmons, S. Buckberry, Dulce B. Vargas-Landín, Daniel Poppe and 5 more. Nature Neuroscience, 2019

750 citations recorded by the source corpus.

Subfields: Molecular Biology, Neurology, Physiology

View Paper: https://www.semanticscholar.org/paper/391adb47e61a3b92ada9dfb5d94a86802ac5d779

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In Physiology

1. Dan Xiao
2. Weifeng Zhang
3. Haibin Xia
4. Q. Mao

Citations in the corpus

• Role of neuroinflammation in neurodegeneration development (2023, result): “Single-nucleus RNA sequencing (snRNA-seq) data on postmortem samples from AD patients and on samples from AD mice model also revealed that the expression of TREM2 was increased in AD pathology.(164,213,214) Further studies suggested that TREM2 was prominently upregulated in microglia around the lesi”