Triple-negative breast cancer: therapeutic options.
By Susan J. Cleator, W. Heller, R. Coombes. The Lancet Oncology, 2007
875 citations recorded by the source corpus.
Subfields: Cancer Research, Genetics, Molecular Biology
View Paper: https://www.semanticscholar.org/paper/38a85fa88a446a8d74afd5b87ac649ac3388fb9c
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In Cancer Research
In Molecular Biology
Citations in the corpus
- High sensitivity of BRCA1-deficient mammary tumors to the PARP inhibitor AZD2281 alone and in combination with platinum drugs (2008, background): “In particular, treatment of patients with triple-negative breast cancers, which account for 15% of all breast cancers (19) and frequently harbor BRCA1 pathway defects (20–23), might be useful, because no targeted therapy exists thus far for this subgroup of breast cancers.”