Nucleosome Arrays Reveal the Two-Start Organization of the Chromatin Fiber

By B. Dorigo, T. Schalch, Alexandra Kulangara, Sylwia Duda, R. Schroeder, T. Richmond. 2004

590 citations recorded by the source corpus.

Subfields: Molecular Biology, Plant Science

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Citations in the corpus

Distinct Structures and Dynamics of Chromatosomes with Different Human Linker Histone Isoforms (2020, background): “Studies of chemically cross-linked nucleosome arrays or nucleosome arrays in crystals suggest the formation of 30-nm fibers with well-defined structures (Dorigo et al., 2004; Garcia-Saez et al., 2018; Song et al., 2014).”
Mapping nucleosome resolution chromosome folding in yeast by Micro-C (2015, unknown): “The structure of a 30 nm fiber is hotly debated, with major models being solenoid and zigzag paths of the beads-on-astring (Dorigo et al., 2004; Ghirlando and Felsenfeld, 2008; Routh et al., 2008; Song et al., 2014; Tremethick, 2007), as well as more recent polymorphic fiber models that incorporate ”
Revisit of reconstituted 30-nm nucleosome arrays reveals an ensemble of dynamic structures (2018, methodology): “A uthor M anuscript A uthor M anuscript A uthor M anuscript A uthor M anuscript provided by Karolin Luger lab) was released from the plasmid by HindIII, XbaI, and DraI digestion (New England Biolabs, MA).”
The H4 Tail Domain Participates in Intra- and Internucleosome Interactions with Protein and DNA during Folding and Oligomerization of Nucleosome Arrays (2008, background): “The H4 tail plays a primary role in promoting the formation of higher-order chromatin structures (13, 19).”
Solution structure(s) of trinucleosomes from contrast variation SAXS (2021, background): “Stacked nucleosomes have been implicated in higher order structure formation based on crystal structures (23,24), and attractive effects have been observed between nucleosomes in solutions using SAXS (25).”
Structural Mechanisms of Nucleosome Recognition by Linker Histones (2015, background): “The nucleosome contains 167 bp DNA centered with the 147 bp ‘‘601’’ positioning sequence (Dorigo et al., 2004; Thåström et al., 2004).”
Ezh1 and Ezh2 maintain repressive chromatin through different mechanisms (2008, result): “…methylation at the global level, Ezh1 was knocked down in NIH 3T3 cells via RNA interference using two oligonucleotides that efficiently target Ezh1 and the results compared to those obtained with another oligonucleotide that was previously characterized as targeting Ezh2 (Etchegaray et al., 2006).”