Treatment of Osteochondritis Dissecans of the Knee with Autologous Chondrocyte Transplantation: Results at Two to Ten Years

By L. Peterson, T. Minas, M. Brittberg, A. Lindahl. Journal of Bone and Joint Surgery. American volume, 2003

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Challenges in tissue engineering (2006, background): “…joints (Honkanen et al. 2003), osteoarthritic knee cartilage (Wakitani et al. 2002), osteochondritis dissecans (Ochi et al. 2002; Peterson et al. 2003), myocardial infarction (Wollert et al. 2004), vascular conduits for extracardiac Fontan operation (Shin’oka et al. 2001; Naito…”
Premature induction of hypertrophy during in vitro chondrogenesis of human mesenchymal stem cells correlates with calcification and vascular invasion after ectopic transplantation in SCID mice. (2006, background): “Autologous chondrocyte transplantation has demonstrated clinical success in the treatment of focal articular cartilage defects (1,4), but donor-site morbidity, dedifferentiation of chondrocytes during expansion, and lack of quality control instruments for the cellular product remain as limitations f”