Millisecond kinetics on a microfluidic chip using nanoliters of reagents.

By Helen Song, R. Ismagilov. Journal of the American Chemical Society, 2003

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Controlled microfluidic interfaces (2005, background): “That is, a given position in the channel will correspond to the same kinetic state, so signals can be collected from several successive droplets and integrated to improve the signal-to-noise ratio, making it possible to monitor even relatively fast reactions with millisecond time resolution or bette”
Droplet based microfluidics (2012, background): “[354, 355], scaling laws of the chaotic advection [356], and”
Microfluidics: Fluid physics at the nanoliter scale (2005, background): “A sedimenting drop in a shear flow Bryden and Brenner, 1999 , a drop driven along a turning microchannel Song, Bringer, et al., 2003; Song and Ismagilov, 2003; Song, Tice, et al., 2003; Tice et al., 2003; Bringer et al., 2004 , and oscillating drops Angilella and Brancher, 2003 all can exhibit…”
Control and detection of chemical reactions in microfluidic systems (2006, background): “Such features, combined with the ability to combine, split and sort droplets, are likely to transform the application of microfluidic systems, and suggest that they would be of use in high-throughput synthesis (due to high sample throughput) and kinetic measurements (due to low sample requirements a”