Interleukin-12 in anti-tumor immunity and immunotherapy.

By M. Colombo, G. Trinchieri. Cytokine & growth factor reviews, 2002

714 citations recorded by the source corpus.

Subfields: Immunology

View Paper: https://www.semanticscholar.org/paper/37c06d345bd4f4c40063b3f69e193265a24d0786

How researchers see this paper

The researchers whose trusted networks rank it highest, strongest advocate first. Every researcher gets a different order.

1. N. Pasche
2. S. Wulhfard
3. Francesca Pretto
4. Elisa Carugati
5. Kristina M. Schwartz
6. E. Garrett-Mayer
7. C. B. Johnson
8. D. Neri

Citations in the corpus

• The Antibody-Based Delivery of Interleukin-12 to the Tumor Neovasculature Eradicates Murine Models of Cancer in Combination with Paclitaxel (2012, background): “For this reason,multiplemechanismshave been reported for the antitumor activity of IL12 (16).”
• Interluekin-12 enhances the function and anti-tumor activity in murine and human CD8+ T cells (2015, background): “The ex vivo dimension of these findings are especially cogent for IL-12 where significant in vivo clinical toxicity [44, 45] has limited the utilization of this promising cytokine and led investigators to look for non-systemic approaches.”